Cardiotoxicity induced by Arsenic Trioxide in a patient with acute promyelocytic leukemia. A case report

Authors

  • Rodolfo Antonio Cruz Rodríguez Universidad de Ciencias Médicas de Cienfuegos, Cuba.
  • Martha del Carmen Acuña Caballero Universidad de Ciencias Médicas de Cienfuegos
  • Lizmaureen Portell Betancourt Universidad de Ciencias Médicas de Cienfuegos
  • Maritza Margarita Cabrera Zamora Hospital General Universitario “Dr. Gustavo Aldereguía Lima”, Cienfuegos

Keywords:

cardiotoxicity, arsenic trioxide, leukemia, electrocardiography

Abstract

Arsenic trioxide has been used in the treatment of acute promyelocytic leukemia with good results in the hematological remission of this malignant hemopathy, but in spite of its effectiveness it can bring various adverse reactions such as cardiotoxicity. The present work had as objective to describe Long QT Syndrome as an adverse reaction to the treatment with arsenic trioxide in a patient with acute promyelocytic leukemia. A case of an 81-year-old patient treated with arsenic trioxide in the Hematology service of the Dr. Gustavo Aldereguía Lima Hospital in Cienfuegos was presented, in which Long QT Syndrome was confirmed by electrocardiography as secondary cardiotoxicity to this treatment.

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Published

2021-08-31

How to Cite

1.
Cruz Rodríguez RA, Acuña Caballero M del C, Portell Betancourt L, Cabrera Zamora MM. Cardiotoxicity induced by Arsenic Trioxide in a patient with acute promyelocytic leukemia. A case report. UNIMED [Internet]. 2021 Aug. 31 [cited 2025 Apr. 19];3(2). Available from: https://revunimed.sld.cu/index.php/revestud/article/view/70

Issue

Section

Casos Clínicos